If all I wanted was to put game on the table and ward off the odd lone asshole, an M6 Scout would be in the running.
Back in the day they could be had from Springfield Armory, made by CZ, for $200. 22LR over 410, meaning that one could shoot rifled 410 slugs for deer... It was my truck and tractor gun for a long time. I am sure the rusty thing is still around here somewhere.
Looks like Chiappa and these guys are still making them
M6 Takedown rifle information page
Speaking of CZ, the old CZ52 pistol is a good C&R gun but the cost is crazy now, like $500!?!?!?!?!?!?